Insulin receptor activation by proinsulin preserves synapses and vision in retinitis pigmentosa
Insulin receptor activation by proinsulin preserves synapses and vision in retinitis pigmentosa
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Synaptic loss, neuronal death, and circuit remodeling are common features of central nervous system neurodegenerative disorders. Retinitis pigmentosa (RP), the leading cause of inherited blindness, is a group of retinal dystrophies characterized by photoreceptor dysfunction and death. The insulin receptor, a key controller of metabolism, also regul...
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Full title
Insulin receptor activation by proinsulin preserves synapses and vision in retinitis pigmentosa
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TN_cdi_doaj_primary_oai_doaj_org_article_b5a24d26701d467ea1eb4c14c34571c4
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b5a24d26701d467ea1eb4c14c34571c4
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-022-04839-0
