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Next generation sequencing based assessment of the alloreactive T cell receptor repertoire in kidney...

Next generation sequencing based assessment of the alloreactive T cell receptor repertoire in kidney...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b5ac0679ce034b42a78d43a9c46c78d5

Next generation sequencing based assessment of the alloreactive T cell receptor repertoire in kidney transplant patients during rejection: a prospective cohort study

About this item

Full title

Next generation sequencing based assessment of the alloreactive T cell receptor repertoire in kidney transplant patients during rejection: a prospective cohort study

Publisher

England: BioMed Central Ltd

Journal title

BMC nephrology, 2019-09, Vol.20 (1), p.346-346, Article 346

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Kidney transplantation is the optimal treatment in end stage renal disease but the allograft survival is still hampered by immune reactions against the allograft. This process is driven by the recognition of allogenic antigens presented to T-cells and their unique T-cell receptor (TCR) via the major histocompatibility complex (MHC), which triggers...

Alternative Titles

Full title

Next generation sequencing based assessment of the alloreactive T cell receptor repertoire in kidney transplant patients during rejection: a prospective cohort study

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b5ac0679ce034b42a78d43a9c46c78d5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b5ac0679ce034b42a78d43a9c46c78d5

Other Identifiers

ISSN

1471-2369

E-ISSN

1471-2369

DOI

10.1186/s12882-019-1541-5

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