The aging mouse CNS is protected by an autophagy-dependent microglia population promoted by IL-34
The aging mouse CNS is protected by an autophagy-dependent microglia population promoted by IL-34
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Microglia harness an unutilized health-promoting potential in age-related neurodegenerative and neuroinflammatory diseases, conditions like progressive multiple sclerosis (MS). Our research unveils an microglia population emerging in the cortical brain regions of aging mice, marked by ERK1/2, Akt, and AMPK phosphorylation patterns and a transcripto...
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The aging mouse CNS is protected by an autophagy-dependent microglia population promoted by IL-34
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TN_cdi_doaj_primary_oai_doaj_org_article_b61d9e7702d14043bf1b0b3ca392caef
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b61d9e7702d14043bf1b0b3ca392caef
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-44556-6