Exploration of Flavonoids as Lead Compounds against Ewing Sarcoma through Molecular Docking, Pharmac...
Exploration of Flavonoids as Lead Compounds against Ewing Sarcoma through Molecular Docking, Pharmacogenomics Analysis, and Molecular Dynamics Simulations
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Switzerland: MDPI AG
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English
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Publisher
Switzerland: MDPI AG
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Ewing sarcoma (ES) is a highly malignant carcinoma prevalent in children and most frequent in the second decade of life. It mostly occurs due to t(11;22) (q24;q12) translocation. This translocation encodes the oncogenic fusion protein EWS/FLI (Friend leukemia integration 1 transcription factor), which acts as an aberrant transcription factor to der...
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Exploration of Flavonoids as Lead Compounds against Ewing Sarcoma through Molecular Docking, Pharmacogenomics Analysis, and Molecular Dynamics Simulations
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TN_cdi_doaj_primary_oai_doaj_org_article_b620cae78ccc453fafb802644d4d8c68
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b620cae78ccc453fafb802644d4d8c68
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules28010414
