SN50 attenuates alveolar hypercoagulation and fibrinolysis inhibition in acute respiratory distress...
SN50 attenuates alveolar hypercoagulation and fibrinolysis inhibition in acute respiratory distress syndrome mice through inhibiting NF-κB p65 translocation
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Author / Creator
Wu, Yanqi , Wang, Yahui , Liu, Bo , Cheng, Yumei , Qian, Hong , Yang, Huilin , Li, Xiang , Yang, Guixia , Zheng, Xinghao and Shen, Feng
Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Contents
It has been confirmed that NF-κB p65 signaling pathway is involved in the regulation of alveolar hypercoagulation and fibrinolysis inhibition in acute respiratory distress syndrome (ARDS). Whether SN50, a NF-κB cell permeable inhibitor, could attenuate alveolar hypercoagulation and fibrinolysis inhibition in ARDS remains to be elucidated.
We exp...
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Full title
SN50 attenuates alveolar hypercoagulation and fibrinolysis inhibition in acute respiratory distress syndrome mice through inhibiting NF-κB p65 translocation
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TN_cdi_doaj_primary_oai_doaj_org_article_b64ed597079144ffb194382766329114
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b64ed597079144ffb194382766329114
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ISSN
1465-993X,1465-9921
E-ISSN
1465-993X,1465-9921
DOI
10.1186/s12931-020-01372-6