TFEB-driven autophagy potentiates TGF-β induced migration in pancreatic cancer cells
TFEB-driven autophagy potentiates TGF-β induced migration in pancreatic cancer cells
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Author / Creator
He, Ruizhi , Wang, Min , Zhao, Chunle , Shen, Ming , Yu, Yahong , He, Li , Zhao, Yan , Chen, Hua , Shi, Xiuhui , Zhou, Min , Pan, Shutao , Liu, Yuhui , Guo, Xingjun , Li, Xu and Qin, Renyi
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Pancreatic ductal adenocarcinoma is one of the most aggressive cancers, with a 5-year survival rate of less than 8%. The complicated tumor microenvironment, particularly TGF-β, provides possible convenience for the progression of PC cells. TGF-β regulates critical cellular processes, including autophagy. However, the mechanism and effects of TGF-β-...
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Full title
TFEB-driven autophagy potentiates TGF-β induced migration in pancreatic cancer cells
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TN_cdi_doaj_primary_oai_doaj_org_article_b664d2ed597140cfadc84678f0422353
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b664d2ed597140cfadc84678f0422353
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ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-019-1343-4