Interaction between genetic predisposition, smoking, and dementia risk: a population-based cohort st...
Interaction between genetic predisposition, smoking, and dementia risk: a population-based cohort study
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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We evaluated whether the association between cigarette smoking and dementia risk is modified by genetic predisposition including apolipoprotein E (APOE) genotype and polygenic risk (excluding the APOE region). We included 193,198 UK Biobank participants aged 60–73 years without dementia at baseline. Of non-APOE-ε4 carriers, 0.89% (95% CI 0.73–1.08%...
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Interaction between genetic predisposition, smoking, and dementia risk: a population-based cohort study
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TN_cdi_doaj_primary_oai_doaj_org_article_b6daf5cefaee4cfdb8f7143e65149d47
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b6daf5cefaee4cfdb8f7143e65149d47
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-92304-x
