Refinement of an ovine-based immunoglobulin therapy against SARS-CoV-2, with comparison of whole IgG...
Refinement of an ovine-based immunoglobulin therapy against SARS-CoV-2, with comparison of whole IgG versus F(ab′)2 fragments
About this item
Full title
Author / Creator
Findlay-Wilson, Stephen , Easterbrook, Linda , Smith, Sandra , Pope, Neville , Aldridge, Matthew , Humphries, Gareth , Schuhmann, Holger , Ngabo, Didier , Rayner, Emma , Otter, Ashley , Coleman, Thomas , Hicks, Bethany , Halkerston, Rachel , Apostolakis, Kostis , Taylor, Stephen , Fotheringham, Susan , Horton, Amanda , CanoCejas, Irene , Wand, Matthew , Tree, Julia A. , Sutton, Mark , Graham, Victoria , Hewson, Roger and Dowall, Stuart
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The development of new therapies against SARS-CoV-2 is required to extend the toolkit of intervention strategies to combat the global pandemic. In this study, hyperimmune plasma from sheep immunised with whole spike SARS-CoV-2 recombinant protein has been used to generate candidate products. In addition to purified IgG, we have refined candidate th...
Alternative Titles
Full title
Refinement of an ovine-based immunoglobulin therapy against SARS-CoV-2, with comparison of whole IgG versus F(ab′)2 fragments
Authors, Artists and Contributors
Author / Creator
Easterbrook, Linda
Smith, Sandra
Pope, Neville
Aldridge, Matthew
Humphries, Gareth
Schuhmann, Holger
Ngabo, Didier
Rayner, Emma
Otter, Ashley
Coleman, Thomas
Hicks, Bethany
Halkerston, Rachel
Apostolakis, Kostis
Taylor, Stephen
Fotheringham, Susan
Horton, Amanda
CanoCejas, Irene
Wand, Matthew
Tree, Julia A.
Sutton, Mark
Graham, Victoria
Hewson, Roger
Dowall, Stuart
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_b6dbbe9b29a843fc82dd0a936c9ba647
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b6dbbe9b29a843fc82dd0a936c9ba647
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-40277-4
