Systemic GLP-1R agonist treatment reverses mouse glial and neurovascular cell transcriptomic aging s...
Systemic GLP-1R agonist treatment reverses mouse glial and neurovascular cell transcriptomic aging signatures in a genome-wide manner
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Pharmacological reversal of brain aging is a long-sought yet challenging strategy for the prevention and treatment of age-related neurodegeneration, due to the diverse cell types and complex cellular pathways impacted by the aging process. Here, we report the genome-wide reversal of transcriptomic aging signatures in multiple major brain cell types...
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Systemic GLP-1R agonist treatment reverses mouse glial and neurovascular cell transcriptomic aging signatures in a genome-wide manner
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TN_cdi_doaj_primary_oai_doaj_org_article_b6e03838a0f54cd39260f2154383d3c8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b6e03838a0f54cd39260f2154383d3c8
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ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-021-02208-9
