Relationship of MMP-14 and TIMP-3 Expression with Macrophage Activation and Human Atherosclerotic Pl...
Relationship of MMP-14 and TIMP-3 Expression with Macrophage Activation and Human Atherosclerotic Plaque Vulnerability
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Publisher
Cairo, Egypt: Hindawi Limiteds
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Language
English
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Publisher
Cairo, Egypt: Hindawi Limiteds
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Contents
Matrix metalloproteinase-14 (MMP-14) promotes vulnerable plaque morphology in mice, whereas tissue inhibitor of metalloproteinases-3 (TIMP-3) overexpression is protective. MMP-14 hi TIMP-3 lo rabbit foam cells are more invasive and more prone to apoptosis than MMP-14 lo TIMP-3 hi cells. We investigated the implications of these findings for human a...
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Full title
Relationship of MMP-14 and TIMP-3 Expression with Macrophage Activation and Human Atherosclerotic Plaque Vulnerability
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TN_cdi_doaj_primary_oai_doaj_org_article_b700e525ba45472391bf6493c4185e94
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b700e525ba45472391bf6493c4185e94
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ISSN
0962-9351,1466-1861
E-ISSN
1466-1861
DOI
10.1155/2014/276457
