Human colon cancer profiles show differential microRNA expression depending on mismatch repair statu...
Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states
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Author / Creator
Sarver, Aaron L , French, Amy J , Borralho, Pedro M , Thayanithy, Venugopal , Oberg, Ann L , Silverstein, Kevin AT , Morlan, Bruce W , Riska, Shaun M , Boardman, Lisa A , Cunningham, Julie M , Subramanian, Subbaya , Wang, Liang , Smyrk, Tom C , Rodrigues, Cecilia MP , Thibodeau, Stephen N and Steer, Clifford J
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Colon cancer arises from the accumulation of multiple genetic and epigenetic alterations to normal colonic tissue. microRNAs (miRNAs) are small, non-coding regulatory RNAs that post-transcriptionally regulate gene expression. Differential miRNA expression in cancer versus normal tissue is a common event and may be pivotal for tumor onset and progre...
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Full title
Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states
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TN_cdi_doaj_primary_oai_doaj_org_article_b75137a880584987bae6c62cd76f6d15
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b75137a880584987bae6c62cd76f6d15
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ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/1471-2407-9-401