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Lnc-PDZD7 contributes to stemness properties and chemosensitivity in hepatocellular carcinoma throug...

Lnc-PDZD7 contributes to stemness properties and chemosensitivity in hepatocellular carcinoma throug...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b76f78b1a96f4662a05b52e9c370bd4a

Lnc-PDZD7 contributes to stemness properties and chemosensitivity in hepatocellular carcinoma through EZH2-mediated ATOH8 transcriptional repression

About this item

Full title

Lnc-PDZD7 contributes to stemness properties and chemosensitivity in hepatocellular carcinoma through EZH2-mediated ATOH8 transcriptional repression

Publisher

England: BioMed Central Ltd

Journal title

Journal of experimental & clinical cancer research, 2019-02, Vol.38 (1), p.92-17

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Hepatocellular carcinoma (HCC) with stemness features are pivotal for tumorigenesis, chemoresistance, and progression. Long non-coding RNAs have been implicated in the regulation of HCC stemness features; however, their mechanisms remain largely unknown. Here, we found that Lnc-PDZD7 is a potential oncogene. We systematically analyzed the clinical...

Alternative Titles

Full title

Lnc-PDZD7 contributes to stemness properties and chemosensitivity in hepatocellular carcinoma through EZH2-mediated ATOH8 transcriptional repression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b76f78b1a96f4662a05b52e9c370bd4a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b76f78b1a96f4662a05b52e9c370bd4a

Other Identifiers

ISSN

0392-9078,1756-9966

E-ISSN

1756-9966

DOI

10.1186/s13046-019-1106-2

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