Transforming Growth Factor Beta Induces Sensory Neuronal Hyperexcitability, and Contributes to Pancr...
Transforming Growth Factor Beta Induces Sensory Neuronal Hyperexcitability, and Contributes to Pancreatic Pain and Hyperalgesia in Rats with Chronic Pancreatitis
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Los Angeles, CA: SAGE Publications
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Language
English
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Publisher
Los Angeles, CA: SAGE Publications
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Background:
Transforming growth factor beta (TGFβ) is upregulated in chronic inflammation, where it plays a key role in wound healing and promoting fibrosis. However, little is known about the peripheral effects of TGFβ on nociception.
Methods:
We tested the in vitro effects of TGFβ1 on the excitability of dorsal root ganglia (DRG) neurons...
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Full title
Transforming Growth Factor Beta Induces Sensory Neuronal Hyperexcitability, and Contributes to Pancreatic Pain and Hyperalgesia in Rats with Chronic Pancreatitis
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TN_cdi_doaj_primary_oai_doaj_org_article_b7cd38f089eb4ac6a6c4ce1b32cb9105
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b7cd38f089eb4ac6a6c4ce1b32cb9105
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ISSN
1744-8069
E-ISSN
1744-8069
DOI
10.1186/1744-8069-8-65