An autophagy enhancer ameliorates diabetes of human IAPP-transgenic mice through clearance of amyloi...
An autophagy enhancer ameliorates diabetes of human IAPP-transgenic mice through clearance of amyloidogenic oligomer
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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We have reported that autophagy is crucial for clearance of amyloidogenic human IAPP (hIAPP) oligomer, suggesting that an autophagy enhancer could be a therapeutic modality against human diabetes with amyloid accumulation. Here, we show that a recently identified autophagy enhancer (MSL-7) reduces hIAPP oligomer accumulation in human induced plurip...
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An autophagy enhancer ameliorates diabetes of human IAPP-transgenic mice through clearance of amyloidogenic oligomer
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TN_cdi_doaj_primary_oai_doaj_org_article_b7f9dbe17f134b678299722702178b09
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b7f9dbe17f134b678299722702178b09
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-20454-z
