A facultative plasminogen-independent thrombolytic enzyme from Sipunculus nudus
A facultative plasminogen-independent thrombolytic enzyme from Sipunculus nudus
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Author / Creator
Tang, Mingqing , Ma, Guoxing , Xu, Chunyan , Yang, Hui , Lin, Hongjun , Bian, Chao , Hu, Chengjia , Lu, Meiling , Chen, Lei , Jie, Wencai , Yue, Zhen , Jian, Jianbo , Sun, Yuqing , Yan, Hui , Zhou, Jingjing , Zhang, Xianying , Liao, Shengye , Li, Zhaofa , Cai, Shuangfeng , Wu, Yaqing , Yang, Kexin , Xiong, Yanan , Zhao, Yonggang , Lv, Zhimin , Xu, Xiaoming , Liu, Chuang , Xin, Pengliang , Ye, Lichao , Cui, Xiuling , Shi, Qiong , Chen, Xi and Xu, Ruian
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Current thrombolytic therapies primarily function by converting plasminogen into plasmin, a process dependent on the fibrin–activator complex. This dependence, coupled with the substantial molecular size of plasmin, constrains its effectiveness in degrading D-dimer and restricts its diffusion within thrombi. Here, we introduce a small facultative p...
Alternative Titles
Full title
A facultative plasminogen-independent thrombolytic enzyme from Sipunculus nudus
Authors, Artists and Contributors
Author / Creator
Ma, Guoxing
Xu, Chunyan
Yang, Hui
Lin, Hongjun
Bian, Chao
Hu, Chengjia
Lu, Meiling
Chen, Lei
Jie, Wencai
Yue, Zhen
Jian, Jianbo
Sun, Yuqing
Yan, Hui
Zhou, Jingjing
Zhang, Xianying
Liao, Shengye
Li, Zhaofa
Cai, Shuangfeng
Wu, Yaqing
Yang, Kexin
Xiong, Yanan
Zhao, Yonggang
Lv, Zhimin
Xu, Xiaoming
Liu, Chuang
Xin, Pengliang
Ye, Lichao
Cui, Xiuling
Shi, Qiong
Chen, Xi
Xu, Ruian
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_b81c3b2c57534004870ae056b4776d6a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b81c3b2c57534004870ae056b4776d6a
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-025-58915-y