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A facultative plasminogen-independent thrombolytic enzyme from Sipunculus nudus

A facultative plasminogen-independent thrombolytic enzyme from Sipunculus nudus

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b81c3b2c57534004870ae056b4776d6a

A facultative plasminogen-independent thrombolytic enzyme from Sipunculus nudus

About this item

Full title

A facultative plasminogen-independent thrombolytic enzyme from Sipunculus nudus

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2025-04, Vol.16 (1), p.3852-19

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Current thrombolytic therapies primarily function by converting plasminogen into plasmin, a process dependent on the fibrin–activator complex. This dependence, coupled with the substantial molecular size of plasmin, constrains its effectiveness in degrading D-dimer and restricts its diffusion within thrombi. Here, we introduce a small facultative p...

Alternative Titles

Full title

A facultative plasminogen-independent thrombolytic enzyme from Sipunculus nudus

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b81c3b2c57534004870ae056b4776d6a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b81c3b2c57534004870ae056b4776d6a

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-025-58915-y

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