Astragaloside IV inhibits lung cancer progression and metastasis by modulating macrophage polarizati...
Astragaloside IV inhibits lung cancer progression and metastasis by modulating macrophage polarization through AMPK signaling
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Author / Creator
Xu, Fei , Cui, Wen-Qiang , Wei, Ying , Cui, Jie , Qiu, Jian , Hu, Ling-Li , Gong, Wei-Yi , Dong, Jing-Cheng and Liu, Bao-Jun
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Accumulating evidence suggests that M2-polarized tumor-associated macrophages (TAMs) play an important role in cancer progression and metastasis, making M2 polarization of TAMs an ever more appealing target for therapeutic intervention. Astragaloside IV (AS-IV), a saponin component isolated from Astragali radix, has been reported to inhibit the inv...
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Full title
Astragaloside IV inhibits lung cancer progression and metastasis by modulating macrophage polarization through AMPK signaling
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TN_cdi_doaj_primary_oai_doaj_org_article_b827f5fde746492abcab025905734a24
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b827f5fde746492abcab025905734a24
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ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-018-0878-0