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Remibrutinib (LOU064): A selective potent oral BTK inhibitor with promising clinical safety and phar...

Remibrutinib (LOU064): A selective potent oral BTK inhibitor with promising clinical safety and phar...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b831d07ed7124764bf42b3d566c92e8a

Remibrutinib (LOU064): A selective potent oral BTK inhibitor with promising clinical safety and pharmacodynamics in a randomized phase I trial

About this item

Full title

Remibrutinib (LOU064): A selective potent oral BTK inhibitor with promising clinical safety and pharmacodynamics in a randomized phase I trial

Publisher

United States: John Wiley & Sons, Inc

Journal title

Clinical and translational science, 2021-09, Vol.14 (5), p.1756-1768

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Safe and effective new oral therapies for autoimmune, allergic, and inflammatory conditions remain a significant therapeutic need. Here, we investigate the human pharmacokinetics, pharmacodynamics (PDs), and safety of the selective, covalent Bruton’s tyrosine kinase (BTK) inhibitor, remibrutinib. Study objectives were explored in randomized single...

Alternative Titles

Full title

Remibrutinib (LOU064): A selective potent oral BTK inhibitor with promising clinical safety and pharmacodynamics in a randomized phase I trial

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b831d07ed7124764bf42b3d566c92e8a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b831d07ed7124764bf42b3d566c92e8a

Other Identifiers

ISSN

1752-8054

E-ISSN

1752-8062

DOI

10.1111/cts.13005

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