Three pools of plasma membrane cholesterol and their relation to cholesterol homeostasis
Three pools of plasma membrane cholesterol and their relation to cholesterol homeostasis
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England: eLife Sciences Publications Ltd
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Language
English
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England: eLife Sciences Publications Ltd
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Contents
When human fibroblasts take up plasma low density lipoprotein (LDL), its cholesterol is liberated in lysosomes and eventually reaches the endoplasmic reticulum (ER) where it inhibits cholesterol synthesis by blocking activation of SREBPs. This feedback protects against cholesterol overaccumulation in the plasma membrane (PM). But how does ER know w...
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Three pools of plasma membrane cholesterol and their relation to cholesterol homeostasis
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TN_cdi_doaj_primary_oai_doaj_org_article_b832cc88db1d4b55bf1b31f351618f64
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b832cc88db1d4b55bf1b31f351618f64
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.02882
