PCGF6 controls neuroectoderm specification of human pluripotent stem cells by activating SOX2 expres...
PCGF6 controls neuroectoderm specification of human pluripotent stem cells by activating SOX2 expression
About this item
Full title
Author / Creator
Lan, Xianchun , Ding, Song , Zhang, Tianzhe , Yi, Ying , Li, Conghui , Jin, Wenwen , Chen, Jian , Liang, Kaiwei , Wang, Hengbin and Jiang, Wei
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Polycomb group (PcG) proteins are known to repress developmental genes during embryonic development and tissue homeostasis. Here, we report that PCGF6 controls neuroectoderm specification of human pluripotent stem cells (PSCs) by activating
SOX2
gene. Human PSCs with PCGF6 depletion display impaired neuroectoderm differentiation coupled with...
Alternative Titles
Full title
PCGF6 controls neuroectoderm specification of human pluripotent stem cells by activating SOX2 expression
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_b85f428bd16441c99b86bb22d58ae234
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b85f428bd16441c99b86bb22d58ae234
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-32295-z
