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Recurrent GNAQ mutation encoding T96S in natural killer/T cell lymphoma

Recurrent GNAQ mutation encoding T96S in natural killer/T cell lymphoma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b8610cbd45064005aa51ebef688a3be5

Recurrent GNAQ mutation encoding T96S in natural killer/T cell lymphoma

About this item

Full title

Recurrent GNAQ mutation encoding T96S in natural killer/T cell lymphoma

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2019-09, Vol.10 (1), p.4209-14, Article 4209

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Natural killer/T cell lymphoma (NKTCL) is a rare and aggressive malignancy with a higher prevalence in Asia and South America. However, the molecular genetic mechanisms underlying NKTCL remain unclear. Here, we identify somatic mutations of
GNAQ
(encoding the T96S alteration of Gαq protein) in 8.7% (11/127) of NKTCL patients, through whole-ex...

Alternative Titles

Full title

Recurrent GNAQ mutation encoding T96S in natural killer/T cell lymphoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b8610cbd45064005aa51ebef688a3be5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b8610cbd45064005aa51ebef688a3be5

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-12032-9

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