Enhanced Expression of Anti-CD19 Chimeric Antigen Receptor in piggyBac Transposon-Engineered T Cells
Enhanced Expression of Anti-CD19 Chimeric Antigen Receptor in piggyBac Transposon-Engineered T Cells
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Publisher
United States: Elsevier Limited
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Language
English
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Publisher
United States: Elsevier Limited
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Contents
Adoptive T cell therapy using chimeric antigen receptor (CAR)-modified T cells is a promising cancer immunotherapy. We previously developed a non-viral method of gene transfer into T cells using a
transposon system to improve the cost-effectiveness of CAR-T cell therapy. Here, we have further improved our technology by a novel culture strategy t...
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Full title
Enhanced Expression of Anti-CD19 Chimeric Antigen Receptor in piggyBac Transposon-Engineered T Cells
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TN_cdi_doaj_primary_oai_doaj_org_article_b87077edcc27440da345a159cfeca963
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b87077edcc27440da345a159cfeca963
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ISSN
2329-0501
E-ISSN
2329-0501
DOI
10.1016/j.omtm.2017.12.003
