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Integrating Network Pharmacology with in vitro Experiments to Validate the Efficacy of Celastrol Aga...

Integrating Network Pharmacology with in vitro Experiments to Validate the Efficacy of Celastrol Aga...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b87de92c7d1c48b586bd2970b4515b95

Integrating Network Pharmacology with in vitro Experiments to Validate the Efficacy of Celastrol Against Hepatocellular Carcinoma Through Ferroptosis

About this item

Full title

Integrating Network Pharmacology with in vitro Experiments to Validate the Efficacy of Celastrol Against Hepatocellular Carcinoma Through Ferroptosis

Publisher

New Zealand: Dove Medical Press Limited

Journal title

Drug design, development and therapy, 2024-01, Vol.18, p.3121-3141

Language

English

Formats

Publication information

Publisher

New Zealand: Dove Medical Press Limited

More information

Scope and Contents

Contents

As a traditional Chinese medicine monomer derived from Tripterygium wilfordii Hook.f. with potential anticancer activity, celastrol can induce ferroptosis in hepatic stellate cells and inhibit their activation to alleviate liver fibrosis. Activation of ferroptosis can effectively inhibit Hepatocellular carcinoma (HCC). Whether celastrol inhibits HC...

Alternative Titles

Full title

Integrating Network Pharmacology with in vitro Experiments to Validate the Efficacy of Celastrol Against Hepatocellular Carcinoma Through Ferroptosis

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b87de92c7d1c48b586bd2970b4515b95

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b87de92c7d1c48b586bd2970b4515b95

Other Identifiers

ISSN

1177-8881

E-ISSN

1177-8881

DOI

10.2147/DDDT.S450324

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