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Chromosome organization by one-sided and two-sided loop extrusion

Chromosome organization by one-sided and two-sided loop extrusion

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b885a93e2e98445689d257f73a3c262e

Chromosome organization by one-sided and two-sided loop extrusion

About this item

Full title

Chromosome organization by one-sided and two-sided loop extrusion

Publisher

England: eLife Sciences Publications Ltd

Journal title

eLife, 2020-04, Vol.9

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

SMC complexes, such as condensin or cohesin, organize chromatin throughout the cell cycle by a process known as loop extrusion. SMC complexes reel in DNA, extruding and progressively growing DNA loops. Modeling assuming two-sided loop extrusion reproduces key features of chromatin organization across different organisms. In vitro single-molecule ex...

Alternative Titles

Full title

Chromosome organization by one-sided and two-sided loop extrusion

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b885a93e2e98445689d257f73a3c262e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b885a93e2e98445689d257f73a3c262e

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.53558

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