Chromosome organization by one-sided and two-sided loop extrusion
Chromosome organization by one-sided and two-sided loop extrusion
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Publisher
England: eLife Sciences Publications Ltd
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Language
English
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Publisher
England: eLife Sciences Publications Ltd
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Contents
SMC complexes, such as condensin or cohesin, organize chromatin throughout the cell cycle by a process known as loop extrusion. SMC complexes reel in DNA, extruding and progressively growing DNA loops. Modeling assuming two-sided loop extrusion reproduces key features of chromatin organization across different organisms. In vitro single-molecule ex...
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Full title
Chromosome organization by one-sided and two-sided loop extrusion
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TN_cdi_doaj_primary_oai_doaj_org_article_b885a93e2e98445689d257f73a3c262e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b885a93e2e98445689d257f73a3c262e
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.53558