Discovery of small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase
Discovery of small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase
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England: Taylor & Francis Ltd
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Language
English
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Publisher
England: Taylor & Francis Ltd
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Contents
Malaria is caused by infection with protozoan parasites of the
genus, which is part of the phylum Apicomplexa. Most organisms in this phylum contain a relic plastid called the apicoplast. The apicoplast genome is replicated by a single DNA polymerase (apPOL), which is an attractive target for anti-malarial drugs. We screened small-molecule libra...
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Full title
Discovery of small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase
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TN_cdi_doaj_primary_oai_doaj_org_article_b8a4728eceee430bb8cbaf513d0499d2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b8a4728eceee430bb8cbaf513d0499d2
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ISSN
1475-6366,1475-6374
E-ISSN
1475-6374
DOI
10.1080/14756366.2022.2070909
