Novel oncolytic chimeric orthopoxvirus causes regression of pancreatic cancer xenografts and exhibit...
Novel oncolytic chimeric orthopoxvirus causes regression of pancreatic cancer xenografts and exhibits abscopal effect at a single low dose
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Pancreatic ductal adenocarcinoma (PDAC) has been increasing by 0.5% per year in the United States. PDAC portends a dismal prognosis and novel therapies are needed. This study describes the generation and characterization of a novel oncolytic chimeric orthopoxvirus for the treatment of pancreatic cancer.
After chimerization and high-throughput sc...
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Novel oncolytic chimeric orthopoxvirus causes regression of pancreatic cancer xenografts and exhibits abscopal effect at a single low dose
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TN_cdi_doaj_primary_oai_doaj_org_article_b8e44900e1b24e1ea7022b6966ec7625
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b8e44900e1b24e1ea7022b6966ec7625
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ISSN
1479-5876
E-ISSN
1479-5876
DOI
10.1186/s12967-018-1483-x
