Increased tumorigenesis associated with loss of the tumor suppressor gene Cadm1
Increased tumorigenesis associated with loss of the tumor suppressor gene Cadm1
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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CADM1 encodes an immunoglobulin superfamily (IGSF) cell adhesion molecule. Inactivation of CADM1, either by promoter hypermethylation or loss of heterozygosity, has been reported in a wide variety of tumor types, thus it has been postulated as a tumor suppressor gene.
We show for the first time that Cadm1 homozygous null mice die significantly f...
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Increased tumorigenesis associated with loss of the tumor suppressor gene Cadm1
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TN_cdi_doaj_primary_oai_doaj_org_article_b922722f13f645a48f55c4e4b0a6a3f4
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b922722f13f645a48f55c4e4b0a6a3f4
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ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/1476-4598-11-29
