DNA methylation profiling reveals a pathological signature that contributes to transcriptional defec...
DNA methylation profiling reveals a pathological signature that contributes to transcriptional defects of CD34+CD15− cells in early chronic‐phase chronic myeloid leukemia
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Author / Creator
Maupetit‐Mehouas, Stéphanie , Court, Franck , Bourgne, Céline , Guerci‐Bresler, Agnès , Cony‐Makhoul, Pascale , Johnson, Hyacinthe , Etienne, Gabriel , Rousselot, Philippe , Guyotat, Denis , Janel, Alexandre , Hermet, Eric , Saugues, Sandrine , Berger, Juliette , Arnaud, Philippe and Berger, Marc G.
Publisher
United States: FEBS Press
Journal title
Language
English
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Publisher
United States: FEBS Press
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Contents
Despite the high efficiency of tyrosine kinase inhibitors (TKI), some patients with chronic myeloid leukemia (CML) will display residual disease that can become resistant to treatment, indicating intraclonal heterogeneity in chronic‐phase CML (CP‐CML). To determine the basis of this heterogeneity, we conducted the first exhaustive characterization...
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Full title
DNA methylation profiling reveals a pathological signature that contributes to transcriptional defects of CD34+CD15− cells in early chronic‐phase chronic myeloid leukemia
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TN_cdi_doaj_primary_oai_doaj_org_article_b9748f2553f944a0a5f7f0ba157e2821
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b9748f2553f944a0a5f7f0ba157e2821
Other Identifiers
ISSN
1574-7891
E-ISSN
1878-0261
DOI
10.1002/1878-0261.12191
