Mice with altered BDNF signaling as models for mood disorders and antidepressant effects
Mice with altered BDNF signaling as models for mood disorders and antidepressant effects
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Publisher
Switzerland: Frontiers Research Foundation
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Language
English
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Publisher
Switzerland: Frontiers Research Foundation
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Contents
Brain-derived neurotrophic factor (BDNF) and its receptor tyrosine kinase TrkB support neuronal survival during development and promote connectivity and plasticity in the adult brain. Decreased BDNF signaling is associated with the pathophysiology of depression and the mechanisms underlying the actions of antidepressant drugs (AD). Several transgen...
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Full title
Mice with altered BDNF signaling as models for mood disorders and antidepressant effects
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TN_cdi_doaj_primary_oai_doaj_org_article_b975122fc898401e81ce353281f06c8e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b975122fc898401e81ce353281f06c8e
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ISSN
1662-5153
E-ISSN
1662-5153
DOI
10.3389/fnbeh.2014.00143
