Chemotherapy increases CDA expression and sensitizes malignant pleural mesothelioma cells to capecit...
Chemotherapy increases CDA expression and sensitizes malignant pleural mesothelioma cells to capecitabine treatment
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The combination of cisplatin and pemetrexed remains the gold standard chemotherapy for malignant pleural mesothelioma (MPM), although resistance and poor response pose a significant challenge. Cytidine deaminase (CDA) is a key enzyme in the nucleotide salvage pathway and is involved in the adaptive stress response to chemotherapy. The cytidine anal...
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Chemotherapy increases CDA expression and sensitizes malignant pleural mesothelioma cells to capecitabine treatment
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TN_cdi_doaj_primary_oai_doaj_org_article_b97b92bc2b4847fca5438e0799a61a42
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b97b92bc2b4847fca5438e0799a61a42
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-69347-x
