Peripherally administered orexin improves survival of mice with endotoxin shock
Peripherally administered orexin improves survival of mice with endotoxin shock
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England: eLife Science Publications, Ltd
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English
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England: eLife Science Publications, Ltd
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Sepsis is a systemic inflammatory response to infection, accounting for the most common cause of death in intensive care units. Here, we report that peripheral administration of the hypothalamic neuropeptide orexin improves the survival of mice with lipopolysaccharide (LPS) induced endotoxin shock, a well-studied septic shock model. The effect is a...
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Peripherally administered orexin improves survival of mice with endotoxin shock
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TN_cdi_doaj_primary_oai_doaj_org_article_b97c3e7543c743b6abdc7a2ccd886b22
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b97c3e7543c743b6abdc7a2ccd886b22
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.21055
