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Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer

Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b9a81dca4e5b4202ba19ac7f9d8afdd3

Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer

About this item

Full title

Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2017-05, Vol.8 (1), p.15081-15081, Article 15081

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Single-cell transcriptome profiling of tumour tissue isolates allows the characterization of heterogeneous tumour cells along with neighbouring stromal and immune cells. Here we adopt this powerful approach to breast cancer and analyse 515 cells from 11 patients. Inferred copy number variations from the single-cell RNA-seq data separate carcinoma c...

Alternative Titles

Full title

Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b9a81dca4e5b4202ba19ac7f9d8afdd3

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b9a81dca4e5b4202ba19ac7f9d8afdd3

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms15081

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