Intragenic recruitment of NF-κB drives splicing modifications upon activation by the oncogene Tax of...
Intragenic recruitment of NF-κB drives splicing modifications upon activation by the oncogene Tax of HTLV-1
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Chronic NF-κB activation in inflammation and cancer has long been linked to persistent activation of NF-κB–responsive gene promoters. However, NF-κB factors also massively bind to gene bodies. Here, we demonstrate that recruitment of the NF-κB factor RELA to intragenic regions regulates alternative splicing upon NF-κB activation by the viral oncoge...
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Intragenic recruitment of NF-κB drives splicing modifications upon activation by the oncogene Tax of HTLV-1
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TN_cdi_doaj_primary_oai_doaj_org_article_b9b58d9a3e674e579917447295972cb5
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b9b58d9a3e674e579917447295972cb5
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-16853-x
