Liver knockout of MCU leads to greater dysregulation of lipid metabolism in MAFLD
Liver knockout of MCU leads to greater dysregulation of lipid metabolism in MAFLD
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Author / Creator
Liao, Qichao , Zhang, Yurou , Pan, Tingli , Sun, Yu , Liu, Siqi , Zhang, Zhiwang , Li, Yixing , Yu, Lin , Luo, Zupeng , Xiao, Yang , Qi, Xinyi , Jiang, Tianyu , Su, Songtao , Liu, Shi , Qi, Xinyu , Li, Xiangling , Damba, Turtushikh , Batchuluun, Khongorzul , Liang, Yunxiao , Wei, Suosu and Zhou, Lei
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Metabolic-associated fatty liver disease (MAFLD) is a common chronic condition that poses a significant threat to human health. Mitochondrial dysfunction, particularly involving the mitochondrial Ca
2+
uniporter (MCU), plays a key role in its pathogenesis. This study aimed to investigate the impact of the MCU gene on hepatic lipid metabolism...
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Full title
Liver knockout of MCU leads to greater dysregulation of lipid metabolism in MAFLD
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TN_cdi_doaj_primary_oai_doaj_org_article_b9b7454b9b6340a6ac485f49eadcdadc
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b9b7454b9b6340a6ac485f49eadcdadc
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-78935-w
