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Self-assembled biodegradable polymeric micelles to improve dapoxetine delivery across the blood-brai...

Self-assembled biodegradable polymeric micelles to improve dapoxetine delivery across the blood-brai...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ba0aa36eed424e9284b606510d199f58

Self-assembled biodegradable polymeric micelles to improve dapoxetine delivery across the blood-brain barrier

About this item

Full title

Self-assembled biodegradable polymeric micelles to improve dapoxetine delivery across the blood-brain barrier

Publisher

New Zealand: Dove Medical Press Limited

Journal title

International journal of nanomedicine, 2018-01, Vol.13, p.3679-3687

Language

English

Formats

Publication information

Publisher

New Zealand: Dove Medical Press Limited

More information

Scope and Contents

Contents

Dapoxetine (DPX) is the drug of choice for the specific treatment of premature ejaculation. DPX is characterized by relatively low bioavailability (42%) and short half-life (1.5 h). The aim of this study was to improve DPX bioavailability and delivery across the blood-brain barrier (BBB) using a nanostructured DPX formulation for improved DPX effic...

Alternative Titles

Full title

Self-assembled biodegradable polymeric micelles to improve dapoxetine delivery across the blood-brain barrier

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ba0aa36eed424e9284b606510d199f58

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ba0aa36eed424e9284b606510d199f58

Other Identifiers

ISSN

1178-2013,1176-9114

E-ISSN

1178-2013

DOI

10.2147/IJN.S168148

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