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Feasibility and potential diagnostic value of [18F]PI-2620 PET in patients with down syndrome and Al...

Feasibility and potential diagnostic value of [18F]PI-2620 PET in patients with down syndrome and Al...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ba2cfbe66a584ca7becb7f7afba05f4e

Feasibility and potential diagnostic value of [18F]PI-2620 PET in patients with down syndrome and Alzheimer’s disease: a case series

About this item

Full title

Feasibility and potential diagnostic value of [18F]PI-2620 PET in patients with down syndrome and Alzheimer’s disease: a case series

Publisher

Switzerland: Frontiers Media S.A

Journal title

Frontiers in neuroscience, 2025-01, Vol.18, p.1505999

Language

English

Formats

Publication information

Publisher

Switzerland: Frontiers Media S.A

More information

Scope and Contents

Contents

Adults with Down Syndrome (DS) have a substantially increased risk for Alzheimer's disease (AD) due to the triplicated amyloid-precursor-protein gene on chromosome 21, resulting in amyloid and tau accumulation. However, tau PET assessments are not sufficiently implemented in DS-AD research or clinical work-up, and second-generation tau tracers such...

Alternative Titles

Full title

Feasibility and potential diagnostic value of [18F]PI-2620 PET in patients with down syndrome and Alzheimer’s disease: a case series

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ba2cfbe66a584ca7becb7f7afba05f4e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ba2cfbe66a584ca7becb7f7afba05f4e

Other Identifiers

ISSN

1662-453X,1662-4548

E-ISSN

1662-453X

DOI

10.3389/fnins.2024.1505999

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