Müller cell degeneration and microglial dysfunction in the Alzheimer's retina
Müller cell degeneration and microglial dysfunction in the Alzheimer's retina
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Author / Creator
Xu, Qinyuan Alis , Boerkoel, Pierre , Hirsch-Reinshagen, Veronica , Mackenzie, Ian R , Hsiung, Ging-Yuek Robin , Charm, Geoffrey , To, Elliott F , Liu, Alice Q , Schwab, Katerina , Jiang, Kailun , Sarunic, Marinko , Beg, Mirza Faisal , Pham, Wellington , Cui, Jing , To, Eleanor , Lee, Sieun and Matsubara, Joanne A
Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Contents
Amyloid beta (Aβ) deposits in the retina of the Alzheimer's disease (AD) eye may provide a useful diagnostic biomarker for AD. This study focused on the relationship of Aβ with macroglia and microglia, as these glial cells are hypothesized to play important roles in homeostasis and clearance of Aβ in the AD retina. Significantly higher Aβ load was...
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Full title
Müller cell degeneration and microglial dysfunction in the Alzheimer's retina
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TN_cdi_doaj_primary_oai_doaj_org_article_ba3b05c1e6ed405c896afaf90c90c798
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ba3b05c1e6ed405c896afaf90c90c798
Other Identifiers
ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-022-01448-y