Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in...
Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma
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Author / Creator
Schick, Markus , Zhang, Le , Maurer, Sabine , Maurer, Hans Carlo , Isaakaidis, Konstandina , Schneider, Lara , Patra, Upayan , Schunck, Kathrin , Rohleder, Elena , Hofstetter, Julia , Baluapuri, Apoorva , Scherger, Anna Katharina , Slotta-Huspenina, Julia , Hettler, Franziska , Weber, Julia , Engleitner, Thomas , Maresch, Roman , Slawska, Jolanta , Lewis, Richard , Istvanffy, Rouzanna , Habringer, Stefan , Steiger, Katja , Baiker, Armin , Oostendorp, Robert A. J. , Miething, Cornelius , Lenhof, Hans-Peter , Bassermann, Florian , Chapuy, Björn , Wirth, Matthias , Wolf, Elmar , Rad, Roland , Müller, Stefan and Keller, Ulrich
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
SUMOylation is a post-translational modification of proteins that regulates these proteins’ localization, turnover or function. Aberrant SUMOylation is frequently found in cancers but its origin remains elusive. Using a genome-wide transposon mutagenesis screen in a MYC-driven B-cell lymphoma model, we here identify the SUMO isopeptidase (or deconj...
Alternative Titles
Full title
Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma
Authors, Artists and Contributors
Author / Creator
Zhang, Le
Maurer, Sabine
Maurer, Hans Carlo
Isaakaidis, Konstandina
Schneider, Lara
Patra, Upayan
Schunck, Kathrin
Rohleder, Elena
Hofstetter, Julia
Baluapuri, Apoorva
Scherger, Anna Katharina
Slotta-Huspenina, Julia
Hettler, Franziska
Weber, Julia
Engleitner, Thomas
Maresch, Roman
Slawska, Jolanta
Lewis, Richard
Istvanffy, Rouzanna
Habringer, Stefan
Steiger, Katja
Baiker, Armin
Oostendorp, Robert A. J.
Miething, Cornelius
Lenhof, Hans-Peter
Bassermann, Florian
Chapuy, Björn
Wirth, Matthias
Wolf, Elmar
Rad, Roland
Müller, Stefan
Keller, Ulrich
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ba5bc46837534430996429dd0c309256
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ba5bc46837534430996429dd0c309256
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-27704-8
