Foxp3 depends on Ikaros for control of regulatory T cell gene expression and function
Foxp3 depends on Ikaros for control of regulatory T cell gene expression and function
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England: eLife Sciences Publications Ltd
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Language
English
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England: eLife Sciences Publications Ltd
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Ikaros is a transcriptional factor required for conventional T cell development, differentiation, and anergy. While the related factors Helios and Eos have defined roles in regulatory T cells (Treg), a role for Ikaros has not been established. To determine the function of Ikaros in the Treg lineage, we generated mice with Treg-specific deletion of...
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Full title
Foxp3 depends on Ikaros for control of regulatory T cell gene expression and function
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TN_cdi_doaj_primary_oai_doaj_org_article_ba76a93665e24702a7a850571913d233
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ba76a93665e24702a7a850571913d233
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.91392
