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Colonic epithelial cathelicidin (LL‐37) expression intensity is associated with progression of color...

Colonic epithelial cathelicidin (LL‐37) expression intensity is associated with progression of color...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ba815979fd8d47278716bcad2a4d676c

Colonic epithelial cathelicidin (LL‐37) expression intensity is associated with progression of colorectal cancer and presence of CD8+ T cell infiltrate

About this item

Full title

Colonic epithelial cathelicidin (LL‐37) expression intensity is associated with progression of colorectal cancer and presence of CD8+ T cell infiltrate

Publisher

Hoboken, USA: John Wiley & Sons, Inc

Journal title

The journal of pathology. Clinical research, 2021-09, Vol.7 (5), p.495-506

Language

English

Formats

Publication information

Publisher

Hoboken, USA: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Colorectal cancer (CRC) remains a leading cause of cancer mortality. Here, we define the colonic epithelial expression of cathelicidin (LL‐37) in CRC. Cathelicidin exerts pleotropic effects including anti‐microbial and immunoregulatory functions. Genetic knockout of cathelicidin led to increased size and number of colorectal tumours in the azoxymet...

Alternative Titles

Full title

Colonic epithelial cathelicidin (LL‐37) expression intensity is associated with progression of colorectal cancer and presence of CD8+ T cell infiltrate

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ba815979fd8d47278716bcad2a4d676c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ba815979fd8d47278716bcad2a4d676c

Other Identifiers

ISSN

2056-4538

E-ISSN

2056-4538

DOI

10.1002/cjp2.222

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