HACE1-mediated NRF2 activation causes enhanced malignant phenotypes and decreased radiosensitivity o...
HACE1-mediated NRF2 activation causes enhanced malignant phenotypes and decreased radiosensitivity of glioma cells
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Author / Creator
Da, Chenxing , Pu, Jun , Liu, Zhe , Wei, Jing , Qu, Yiping , Wu, Yongxing , Shi, Bingyin , Yang, Jian , He, Nongyue and Hou, Peng
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
HACE1, an E3 ubiquitin-protein ligase, is frequently inactivated and has been evidenced as a putative tumor suppressor in different types of cancer. However, its role in glioma remains elusive. Here, we observed increased expression of HACE1 in gliomas related to control subjects, and found a strong correlation of high HACE1 expression with poor pr...
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Full title
HACE1-mediated NRF2 activation causes enhanced malignant phenotypes and decreased radiosensitivity of glioma cells
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TN_cdi_doaj_primary_oai_doaj_org_article_ba8891b4a6314699b53fa292268d5610
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ba8891b4a6314699b53fa292268d5610
Other Identifiers
ISSN
2059-3635,2095-9907
E-ISSN
2059-3635
DOI
10.1038/s41392-021-00793-z
