Synthesis and contractile activity of substituted 1,2,3,4-tetrahydroisoquinolines
Synthesis and contractile activity of substituted 1,2,3,4-tetrahydroisoquinolines
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
A series of different 1-monosubstituted and 1,1-disubstituted 1,2,3,4-tetrahydro-isoquinolines was synthesized in high yields from different ketoamides. We have developed a convenient method for the synthesis of disubstituted derivatives by interaction of ketoamides with organomagnesium compounds, followed by cyclization in the presence of catalyti...
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Full title
Synthesis and contractile activity of substituted 1,2,3,4-tetrahydroisoquinolines
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TN_cdi_doaj_primary_oai_doaj_org_article_bab2b760f0e24b33bac1157fd20221ef
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bab2b760f0e24b33bac1157fd20221ef
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules16087019
