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An Alignment-Independent 3D-QSAR Study of FGFR2 Tyrosine Kinase Inhibitors

An Alignment-Independent 3D-QSAR Study of FGFR2 Tyrosine Kinase Inhibitors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bb32953117b84f9197a47793e9f1812d

An Alignment-Independent 3D-QSAR Study of FGFR2 Tyrosine Kinase Inhibitors

About this item

Full title

An Alignment-Independent 3D-QSAR Study of FGFR2 Tyrosine Kinase Inhibitors

Publisher

Tabriz: Tabriz University of Medical Sciences

Journal title

Advanced pharmaceutical bulletin, 2017-09, Vol.7 (3), p.409-418

Language

English

Formats

Publication information

Publisher

Tabriz: Tabriz University of Medical Sciences

More information

Scope and Contents

Contents

FGFR2 as one of the important factors on the surface of CAFs is overexpressed in some human cancers including stomach, pancreas, and breast. [...]mutations of this receptor can lead to intrinsically active form of FGFR2 reported in endometrial and lung cancers.5 Inhibition of RTKs as a promising target in treatment of different kinds of cancers has...

Alternative Titles

Full title

An Alignment-Independent 3D-QSAR Study of FGFR2 Tyrosine Kinase Inhibitors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_bb32953117b84f9197a47793e9f1812d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bb32953117b84f9197a47793e9f1812d

Other Identifiers

ISSN

2228-5881

E-ISSN

2251-7308

DOI

10.15171/apb.2017.049

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