Matrix Metalloproteinase-8 Augments Bacterial Clearance in a Juvenile Sepsis Model
Matrix Metalloproteinase-8 Augments Bacterial Clearance in a Juvenile Sepsis Model
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Publisher
England: BioMed Central
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Language
English
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England: BioMed Central
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Contents
Genetic ablation or pharmacologic inhibition of matrix metalloproteinase-8 (
) improves survival in an adult murine sepsis model. Because developmental age influences the host inflammatory response, we hypothesized that developmental age influences the role of
in sepsis. First, we compared sepsis survival between wild type (WT, C57BL/6) and
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Full title
Matrix Metalloproteinase-8 Augments Bacterial Clearance in a Juvenile Sepsis Model
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TN_cdi_doaj_primary_oai_doaj_org_article_bb6ee77a25884b63ba7c9179b3e415c4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bb6ee77a25884b63ba7c9179b3e415c4
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ISSN
1076-1551
E-ISSN
1528-3658
DOI
10.2119/molmed.2016.00058