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Matrix Metalloproteinase-8 Augments Bacterial Clearance in a Juvenile Sepsis Model

Matrix Metalloproteinase-8 Augments Bacterial Clearance in a Juvenile Sepsis Model

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bb6ee77a25884b63ba7c9179b3e415c4

Matrix Metalloproteinase-8 Augments Bacterial Clearance in a Juvenile Sepsis Model

About this item

Full title

Matrix Metalloproteinase-8 Augments Bacterial Clearance in a Juvenile Sepsis Model

Publisher

England: BioMed Central

Journal title

Molecular medicine (Cambridge, Mass.), 2016-08, Vol.22 (1), p.455-463

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

Genetic ablation or pharmacologic inhibition of matrix metalloproteinase-8 (
) improves survival in an adult murine sepsis model. Because developmental age influences the host inflammatory response, we hypothesized that developmental age influences the role of
in sepsis. First, we compared sepsis survival between wild type (WT, C57BL/6) and

Alternative Titles

Full title

Matrix Metalloproteinase-8 Augments Bacterial Clearance in a Juvenile Sepsis Model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_bb6ee77a25884b63ba7c9179b3e415c4

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bb6ee77a25884b63ba7c9179b3e415c4

Other Identifiers

ISSN

1076-1551

E-ISSN

1528-3658

DOI

10.2119/molmed.2016.00058

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