Rbf/E2F1 control growth and endoreplication via steroid-independent Ecdysone Receptor signalling in...
Rbf/E2F1 control growth and endoreplication via steroid-independent Ecdysone Receptor signalling in Drosophila prostate-like secondary cells
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United States: Public Library of Science
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English
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United States: Public Library of Science
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In prostate cancer, loss of the tumour suppressor gene,
Retinoblastoma
(
Rb
), and consequent activation of transcription factor E2F1 typically occurs at a late-stage of tumour progression. It appears to regulate a switch to an androgen-independent form of cancer, castration-resistant prostate cancer (CRPC), which frequently still requi...
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Rbf/E2F1 control growth and endoreplication via steroid-independent Ecdysone Receptor signalling in Drosophila prostate-like secondary cells
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TN_cdi_doaj_primary_oai_doaj_org_article_bba9b34ae61a425293f1b4d2428048d7
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bba9b34ae61a425293f1b4d2428048d7
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1010815
