Frequent Germline and Somatic Single Nucleotide Variants in the Promoter Region of the Ribosomal RNA...
Frequent Germline and Somatic Single Nucleotide Variants in the Promoter Region of the Ribosomal RNA Gene in Japanese Lung Adenocarcinoma Patients
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Author / Creator
Ohashi, Riuko , Umezu, Hajime , Sato, Ayako , Abé, Tatsuya , Kondo, Shuhei , Daigo, Kenji , Sato, Seijiro , Hara, Norikazu , Miyashita, Akinori , Ikeuchi, Takeshi , Motoyama, Teiichi , Kishi, Masashi , Nagaoka, Tadahiro , Horiuchi, Keiko , Shiga, Atsushi , Okuda, Shujiro , Sekiya, Tomoki , Ohtsubo, Aya , Ichikawa, Kosuke , Kagamu, Hiroshi , Kikuchi, Toshiaki , Watanabe, Satoshi , Tanuma, Jun-Ichi , Schraml, Peter , Hamakubo, Takao , Tsuchida, Masanori and Ajioka, Yoichi
Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publication information
Publisher
Switzerland: MDPI AG
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More information
Scope and Contents
Contents
Ribosomal RNA (rRNA), the most abundant non-coding RNA species, is a major component of the ribosome. Impaired ribosome biogenesis causes the dysfunction of protein synthesis and diseases called "ribosomopathies," including genetic disorders with cancer risk. However, the potential role of rRNA gene (rDNA) alterations in cancer is unknown. We inves...
Alternative Titles
Full title
Frequent Germline and Somatic Single Nucleotide Variants in the Promoter Region of the Ribosomal RNA Gene in Japanese Lung Adenocarcinoma Patients
Authors, Artists and Contributors
Author / Creator
Umezu, Hajime
Sato, Ayako
Abé, Tatsuya
Kondo, Shuhei
Daigo, Kenji
Sato, Seijiro
Hara, Norikazu
Miyashita, Akinori
Ikeuchi, Takeshi
Motoyama, Teiichi
Kishi, Masashi
Nagaoka, Tadahiro
Horiuchi, Keiko
Shiga, Atsushi
Okuda, Shujiro
Sekiya, Tomoki
Ohtsubo, Aya
Ichikawa, Kosuke
Kagamu, Hiroshi
Kikuchi, Toshiaki
Watanabe, Satoshi
Tanuma, Jun-Ichi
Schraml, Peter
Hamakubo, Takao
Tsuchida, Masanori
Ajioka, Yoichi
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_bbb0d54a6cf148f4a62a2177a1c8183c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bbb0d54a6cf148f4a62a2177a1c8183c
Other Identifiers
ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells9112409