Trajectory and Functional Analysis of PD‐1high CD4+CD8+ T Cells in Hepatocellular Carcinoma by Singl...
Trajectory and Functional Analysis of PD‐1high CD4+CD8+ T Cells in Hepatocellular Carcinoma by Single‐Cell Cytometry and Transcriptome Sequencing
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Author / Creator
Zheng, Bo , Wang, Dongfang , Qiu, Xinyao , Luo, Guijuan , Wu, Tong , Yang, Shuai , Li, Zhixuan , Zhu, Yanjing , Wang, Shan , Wu, Rui , Sui, Chengjun , Gu, Ziqi , Shen, Siyun , Jeong, Seogsong , Wu, Xuan , Gu, Jin , Wang, Hongyang and Chen, Lei
Publisher
Hoboken: John Wiley and Sons Inc
Journal title
Language
English
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Publisher
Hoboken: John Wiley and Sons Inc
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Contents
The spatial heterogeneity of immune microenvironment in hepatocellular carcinoma (HCC) remains elusive. Here, a single‐cell study involving 17 432 600 immune cells of 39 matched HCC (T), nontumor (N), and leading‐edge (L) specimens by mass cytometry is conducted. The tumor‐associated CD4/CD8 double‐positive T (DPT) cells are found enriched in L reg...
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Full title
Trajectory and Functional Analysis of PD‐1high CD4+CD8+ T Cells in Hepatocellular Carcinoma by Single‐Cell Cytometry and Transcriptome Sequencing
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_bbdc4fdf3a334538ac7cadb2166d9a63
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bbdc4fdf3a334538ac7cadb2166d9a63
Other Identifiers
ISSN
2198-3844
E-ISSN
2198-3844
DOI
10.1002/advs.202000224
