A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy
A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy
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Author / Creator
Chitiprolu, Maneka , Jagow, Chantal , Tremblay, Veronique , Bondy-Chorney, Emma , Paris, Geneviève , Savard, Alexandre , Palidwor, Gareth , Barry, Francesca A. , Zinman, Lorne , Keith, Julia , Rogaeva, Ekaterina , Robertson, Janice , Lavallée-Adam, Mathieu , Woulfe, John , Couture, Jean-François , Côté, Jocelyn and Gibbings, Derrick
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Mutations in proteins like FUS which cause Amyotrophic Lateral Sclerosis (ALS) result in the aberrant formation of stress granules while ALS-linked mutations in other proteins impede elimination of stress granules. Repeat expansions in C9ORF72, the major cause of ALS, reduce C9ORF72 levels but how this impacts stress granules is uncertain. Here, we...
Alternative Titles
Full title
A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy
Authors, Artists and Contributors
Author / Creator
Jagow, Chantal
Tremblay, Veronique
Bondy-Chorney, Emma
Paris, Geneviève
Savard, Alexandre
Palidwor, Gareth
Barry, Francesca A.
Zinman, Lorne
Keith, Julia
Rogaeva, Ekaterina
Robertson, Janice
Lavallée-Adam, Mathieu
Woulfe, John
Couture, Jean-François
Côté, Jocelyn
Gibbings, Derrick
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_bbf18a982cd84beb955aa489eecafe37
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bbf18a982cd84beb955aa489eecafe37
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-05273-7