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A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy

A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bbf18a982cd84beb955aa489eecafe37

A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy

About this item

Full title

A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2018-07, Vol.9 (1), p.2794-18, Article 2794

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Mutations in proteins like FUS which cause Amyotrophic Lateral Sclerosis (ALS) result in the aberrant formation of stress granules while ALS-linked mutations in other proteins impede elimination of stress granules. Repeat expansions in C9ORF72, the major cause of ALS, reduce C9ORF72 levels but how this impacts stress granules is uncertain. Here, we...

Alternative Titles

Full title

A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_bbf18a982cd84beb955aa489eecafe37

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bbf18a982cd84beb955aa489eecafe37

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-018-05273-7

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