Higher proportions of CD39+ tumor-resident cytotoxic T cells predict recurrence-free survival in pat...
Higher proportions of CD39+ tumor-resident cytotoxic T cells predict recurrence-free survival in patients with stage III melanoma treated with adjuvant immunotherapy
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Attrill, Grace Heloise , Owen, Carina N , Ahmed, Tasnia , Vergara, Ismael A , Colebatch, Andrew J , Conway, Jordan W , Nahar, Kazi J , Thompson, John F , Pires da Silva, Ines , Carlino, Matteo S , Menzies, Alexander M , Lo, Serigne , Palendira, Umaimainthan , Scolyer, Richard A , Long, Georgina V and Wilmott, James S
Publisher
England: BMJ Publishing Group Ltd
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English
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England: BMJ Publishing Group Ltd
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BackgroundAdjuvant immune checkpoint inhibitor (ICI) immunotherapies have significantly reduced the recurrence rate in high-risk patients with stage III melanoma compared with surgery alone. However, 48% of anti-PD-1-treated patients will develop recurrent disease within 4 years. There is a need to identify biomarkers of recurrence after adjuvant I...
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Higher proportions of CD39+ tumor-resident cytotoxic T cells predict recurrence-free survival in patients with stage III melanoma treated with adjuvant immunotherapy
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TN_cdi_doaj_primary_oai_doaj_org_article_bc42aa6825a44fdb8db135c1150e97e4
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bc42aa6825a44fdb8db135c1150e97e4
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ISSN
2051-1426
E-ISSN
2051-1426
DOI
10.1136/jitc-2022-004771