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Circulating histones contribute to monocyte and MDW alterations as common mediators in classical and...

Circulating histones contribute to monocyte and MDW alterations as common mediators in classical and...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bc4434ac9ae943d5bf84635777800156

Circulating histones contribute to monocyte and MDW alterations as common mediators in classical and COVID-19 sepsis

About this item

Full title

Circulating histones contribute to monocyte and MDW alterations as common mediators in classical and COVID-19 sepsis

Publisher

London: BioMed Central Ltd

Journal title

Critical care (London, England), 2022-08, Vol.26 (1), p.1-260, Article 260

Language

English

Formats

Publication information

Publisher

London: BioMed Central Ltd

More information

Scope and Contents

Contents

Objective Histone proteins are physiologically involved in DNA packaging and gene regulation but are extracellularly released by neutrophil/monocyte extracellular traps and mediate thrombo-inflammatory pathways, associated to the severity of many human pathologies, including bacterial/fungal sepsis and COVID-19. Prominent and promising laboratory f...

Alternative Titles

Full title

Circulating histones contribute to monocyte and MDW alterations as common mediators in classical and COVID-19 sepsis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_bc4434ac9ae943d5bf84635777800156

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bc4434ac9ae943d5bf84635777800156

Other Identifiers

ISSN

1364-8535

E-ISSN

1364-8535,1366-609X,1466-609X

DOI

10.1186/s13054-022-04138-2

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