Generation of a rod-specific NRL reporter line in human pluripotent stem cells
Generation of a rod-specific NRL reporter line in human pluripotent stem cells
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Reporter lines generated in human pluripotent stem cells can be highly useful for the analysis of specific cell types and lineages in live cultures. We created the first human rod reporter line using CRISPR/Cas9 genome editing to replace one allele of the Neural Retina Leucine zipper (
NRL
) gene with an
eGFP
transgene in the WA09 human...
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Full title
Generation of a rod-specific NRL reporter line in human pluripotent stem cells
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TN_cdi_doaj_primary_oai_doaj_org_article_bc6bee677a18423c99acf52dbb951ec4
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bc6bee677a18423c99acf52dbb951ec4
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-20813-3
